Tadalafil: what it does, how to use it, and how to buy safely

Tadalafil is a prescription medicine most people know for treating erectile dysfunction (ED). A key fact: tadalafil can work up to 36 hours, which is why many call it the "weekend pill." It’s also approved for benign prostatic hyperplasia (BPH) and pulmonary arterial hypertension (as Adcirca).

How to use tadalafil safely

There are two common ways people take tadalafil. For occasional use, doctors often recommend 10 mg taken at least 30 minutes before sex; doses can be adjusted to 20 mg or lowered to 5 mg based on effect and side effects. For daily use—helpful if you expect frequent sexual activity or have BPH—typical doses are 2.5–5 mg once a day. For pulmonary arterial hypertension the usual dose is higher and always guided by a specialist.

Start low if you’re unsure and talk to your doctor about other health issues. Common side effects include headache, flushing, back pain, indigestion, nasal congestion and muscle aches. Rare but serious reactions are sudden vision or hearing loss, chest pain, fainting, or an erection lasting over four hours (priapism). If you get any of those, seek emergency care.

Watch drug interactions. Never take tadalafil with nitrates (nitroglycerin) — the combo can dangerously drop blood pressure. Be cautious with alpha-blockers, high blood pressure meds, and strong CYP3A4 inhibitors like ketoconazole or ritonavir, which raise tadalafil levels. Alcohol can worsen dizziness and lower blood pressure, so limit drinks when using the medicine.

Buying tadalafil online — what to check

Tadalafil is a prescription drug, so any safe online pharmacy should ask for a prescription. Before you order, confirm the site is licensed, shows a real address and pharmacist contact, and uses HTTPS. Beware of prices that look too good to be true or sellers who skip the prescription step. Look for third-party seals, clear return policies, and verified customer service.

If you’re comparing tadalafil to sildenafil (Viagra): tadalafil lasts much longer and offers more spontaneity; sildenafil usually acts faster but wears off in a few hours. Which is better depends on your needs and medical profile—discuss with your prescriber.

Storage is simple: keep tablets in a dry place at room temperature, out of reach of kids. If you miss a daily dose, take it as soon as you remember but don’t double up that day. Keep all follow-ups with your doctor, especially if you have heart disease, low blood pressure, kidney or liver problems.

Want a quick checklist before you buy online? 1) Prescription required, 2) Pharmacy license and contact info, 3) Secure checkout (HTTPS), 4) Clear dosing info and pharmacist access, 5) Real customer support. Follow those steps and you’ll cut risk while getting the medicine you need.

Top 7 Alternatives to Cialis: Exploring Your Options
Angus MacAlister 4 March 2025
Top 7 Alternatives to Cialis: Exploring Your Options

If Cialis isn't the right fit for you, several alternative treatments for erectile dysfunction could be worth considering. From Alprostadil suppositories to Tadalafil, each alternative offers its own pros and cons. This article delves into seven options, helping you weigh the benefits and drawbacks. Discover which treatment might be the best match for your needs and lifestyle.